Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9917150 | 0.87 | LMNA (0.47) | NPSR1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL4303475 | 0.86 | SMN1; SMN2 (0.41) | NPSR1MEN1KMT2AMAPTTP53 | |
| SCHEMBL5671532 | 0.78 | MEN1 (0.36) | NPSR1MEN1KMT2AMAPTPOLB | |
| SCHEMBL10603016 | 0.77 | MEN1 (0.35) | NPSR1MEN1KMT2AMAPTLATS1 | |
| SCHEMBL2906382 | 0.77 | NPSR1 (0.35) | NPSR1MEN1KMT2AMAPTTP53 | |
| SCHEMBL11617310 | 0.77 | NPSR1 (0.32) | NPSR1MEN1KMT2AMAPTLATS1 | |
| SCHEMBL16657115 | 0.74 | SMN1; SMN2 (0.54) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL7870521 | 0.72 | LATS1 (0.34) | NPSR1MAPTLATS1LATS2SMN1; SMN2 | |
| SCHEMBL20355508 | 0.71 | POLB (0.38) | MAPTTP53POLBLATS1LATS2 | |
| SCHEMBL23960455 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7628936-B2 | Mixture of steric hindred amine compound with magnesium and zinc salt; photostability; heat and oxidation resistance; for polymers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-12-08 | — | — | US | disclosed |