Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5119502 | 0.74 | ELANE (0.51) | ELANEPDE5A | |
| SCHEMBL813684 | 0.73 | METAP2 (0.30) | — | |
| SCHEMBL4458738 | 0.72 | ELANE (0.42) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL13185023 | 0.72 | ELANE (0.42) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL3354495 | 0.71 | ELANE (0.56) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL913440 | 0.68 | PDE5A (0.30) | ELANEPDE5A | |
| SCHEMBL12102096 | 0.68 | PDE5A (0.47) | KDM4EALDH1A1PDE5A | |
| SCHEMBL1964870 | 0.68 | ELANE (0.61) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL27109651 | 0.67 | PDE5A (0.31) | PDE5A | |
| SCHEMBL757536 | 0.65 | ELANE (0.72) | ELANEKDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298821-A1 | HYDROXY AND ALKOXY SUBSTITUTED IH-IMIDAZONAPHTHYRIDINES AND METHODS | PFIZER INC. | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298821-A1 | HYDROXY AND ALKOXY SUBSTITUTED IH-IMIDAZONAPHTHYRIDINES AND METHODS | IL2, IL4, IFNG | ELANE 1075/4885KDM4E 2756/4885MEN1 3637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.