Styrene

Styrene

SCHEMBL3717971

C=C(CC)c1ccccc1.C=Cc1ccccc1

nearest known ligand 0.54

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
TSHR P16473 1/20 0.54
MAOA P21397 6/20 0.41
MAOB P27338 6/20 0.41
ATM Q13315 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
AKT1 P31749 1/20 0.36
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1503077 0.90 ALDH1A1 (0.42) ALDH1A1TSHRMAOAMAOBCES2
SCHEMBL5038514 0.88 ALDH1A1 (0.41) ALDH1A1TSHRMAOAMAOBTAS1R3
SCHEMBL8060532 0.86 TAS1R3 (0.49) ALDH1A1TSHRTAS1R3TAS1R1TDP1
SCHEMBL14958 0.85 MAOA (0.52) ALDH1A1MAOAMAOBATMCES2
Styrene SCHEMBL27084529 0.85 ALDH1A1 (0.50) ALDH1A1TSHRMAOAMAOBCES2
SCHEMBL7560324 0.85 MAOA (0.41) ALDH1A1MAOAMAOBATMCES2
SCHEMBL14992845 0.83 TDP1 (0.47) ALDH1A1TSHRTAS1R3TAS1R1TP53
Styrene SCHEMBL1359243 0.82 ALDH1A1 (0.56) ALDH1A1TSHRATMTAS1R3TAS1R1
Styrene SCHEMBL5287077 0.82 ALDH1A1 (0.47) ALDH1A1TSHRMAOAMAOBCES2
SCHEMBL9009925 0.81 KDM1A (0.39) ALDH1A1TSHRMAOAMAOBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120172614-A1 METHOD FOR THE MANUFACTURE OF DIALKYL PHOSPHITES STRAITMARK HOLDING AG (CH) 2012-07-05 US claimed
CN-102448973-A Process for the preparation of dialkylphosphites STRAITMARK HOLDING AG 2012-05-09 CN claimed
WO-2010136575-A1 METHOD FOR THE MANUFACTURE OF DIALKYL PHOSPHITES STRAITMARK HOLDING AG (CH) 2010-12-02 WO claimed
US-7169298-B2 Method and apparatus for separating polynucleotides using monolithic capillary columns TRANSGENOMIC, INC. (US) 2007-01-30 US disclosed
CN-1685005-A Oxygen-absorbing resin composition and laminate TOYO SEIKAN KAISHA LTD (JP) 2005-10-19 CN disclosed
US-20020088753-A1 Method and apparatus for separating polynucleotides using monolithic capillary columns THIRD SECURITY SENIOR STAFF 2008 LLC 2002-07-11 US disclosed
EP-1104773-A1 Process for the preparation of monodispersed adsorber resins and use thereof BAYER AG (DE) 2001-06-06 EP disclosed
US-5591805-A MALEIC ANHYDRIDE-CYCLOOCTENE COPOLYMER CURED WITH HYDROXY, ACID, EPOXY OR AMINE COMPOUNDS, CLEAR COATS THE SHERWIN-WILLIAMS COMPANY (US) 1997-01-07 US disclosed
EP-0573070-A2 Process for purifying phenol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-12-08 EP disclosed
US-4946819-A Phosphorus-antimony-containing catalyst for oxidation NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1990-08-07 US disclosed