Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20952824 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HPGDPOLBMAPTLMNA | |
| SCHEMBL29131548 | 0.78 | CA2 (0.34) | CA2CA9 | |
| SCHEMBL21538015 | 0.76 | CA2 (0.39) | CA2CA9 | |
| SCHEMBL13828918 | 0.76 | — | — | |
| SCHEMBL24313178 | 0.73 | ALDH1A1 (0.40) | ALDH1A1CA2HPGDPOLBMAPT | |
| SCHEMBL14328149 | 0.73 | — | — | |
| SCHEMBL22032437 | 0.72 | CYP3A4 (0.40) | ALDH1A1CA2CA9MAPTLMNA | |
| SCHEMBL22032438 | 0.72 | CYP3A4 (0.40) | ALDH1A1CA2CA9MAPTLMNA | |
| SCHEMBL21546112 | 0.72 | — | — | |
| SCHEMBL3903736 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023201008-A1 | COMPOSITIONS AND METHODS FOR LOCALIZED DELIVERY OF CYTOKINES FOR ADOPTIVE CELL THERAPY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-10-19 | — | — | WO | disclosed |
| US-20210284776-A1 | COMPOSITIONS AND METHODS FOR LABELING AND MODULATION OF CELLS IN VITRO AND IN VIVO | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-09-16 | — | — | US | disclosed |
| WO-2021155297-A1 | METHODS FOR LABELING AND TARGETING CELLS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-08-05 | — | — | WO | disclosed |
| CN-111138417-B | Triazole modified 5-fluoro-2, 4-pyrimidinediamine compound and application thereof | 浙江工业大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-111138417-A | Triazole modified 5-fluoro-2, 4-pyrimidinediamine compound and application thereof | 浙江工业大学 | 2020-05-12 | — | — | CN | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-8779008-B2 | Polymeric micelles for drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130195987-A1 | POLYMERIC MICELLES FOR DRUG DELIVERY | INTEZYNE TECHNOLOGIES, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2013-05-23 | — | — | US | disclosed |
| US-8367713-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-02-05 | — | — | US | disclosed |
| US-7638558-B2 | drug loaded micelle of a triblock polymer tert-butylphenylsilylpropene-polyethylene glycol-b-poly(tert-butylaspartic acid-b-polyphenylalanine-copoly( tert-buyltyrosine) has a drug-loaded inner core, a crosslinked outer core, and a hydrophilic shell | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-7618944-B2 | Encapsulating in micelle which is a block copolymer containing hydrophilic and hydrophobic blocks | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-11-17 | — | — | US | disclosed |
| WO-2009131654-A2 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
| US-7601796-B2 | polyamideether copolymer has a hydrophilic polyethylene glycol and a hydrophobic polyamino acid blocks; modified polyethylene glycol homopolymer; forming conjugate polymer drug; resin peptides; use in pharmaceutically acceptable compositions | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-20090092554-A1 | ENCAPSULATED CONTRAST AGENTS | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-20080274173-A1 | Copolymer of crosslinkable or crosslinked poly(amino acid block), and a hydrophobic D,L-mixed poly(amino acid) block; an inner core, crosslinked outer core, a hydrophilic shell; improved in vivo circulation time; drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080274965-A1 | ENCAPSULATED AMYLOID-BETA PEPTIDES | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080035243-A1 | Covalent modification of metal surfaces | INTEZYNE TECHNOLOGIES (US) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080035243-A1 | Covalent modification of metal surfaces | ITGAL, ITGA1, ITGA5 | ALDH1A1 933/4885CA2 320/4885CA9 1058/4885 |
| US-20080274965-A1 | ENCAPSULATED AMYLOID-BETA PEPTIDES | IAPP, APP, TTR | ALDH1A1 4688/4885CA2 2809/4885CA9 2189/4885 |
| US-20130195987-A1 | POLYMERIC MICELLES FOR DRUG DELIVERY | ABCB4, CLTB, CD47 | ALDH1A1 4414/4885CA2 2651/4885CA9 1750/4885 |
| US-20210284776-A1 | COMPOSITIONS AND METHODS FOR LABELING AND MODULATION OF CELLS IN VITRO AND IN VIVO | CD47, LY6K, CD68 | ALDH1A1 1059/4885CA2 4213/4885CA9 2626/4885 |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | ALDH1A1 3079/4885CA2 3572/4885CA9 2293/4885 |
| US-20090092554-A1 | ENCAPSULATED CONTRAST AGENTS | LIPA, LPXN, CD47 | ALDH1A1 3588/4885CA2 1314/4885CA9 143/4885 |
| US-20080274173-A1 | Copolymer of crosslinkable or crosslinked poly(amino acid block), and a hydrophobic D,L-mixed poly(amino acid) block; an inner core, crosslinked outer core, a hydrophilic shell; improved in vivo circulation time; drug delivery | CLTB, SLC1A5, CLTA | ALDH1A1 3966/4885CA2 1865/4885CA9 2123/4885 |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | ALDH1A1 3079/4885CA2 3572/4885CA9 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.