Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31517605 | 1.00 | NAPRT (0.57) | NAPRTMAPTKDM4EALDH1A1LMNA | |
| Biphenyl SCHEMBL27934333 | 0.95 | NAPRT (0.51) | NAPRTMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL31517401 | 0.87 | ERCC5 (0.47) | NAPRTMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL3814933 | 0.86 | RAB9A (0.63) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL31517664 | 0.83 | RAB9A (0.46) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL31517715 | 0.83 | MAPT (0.50) | NAPRTMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL12369718 | 0.78 | CYP2A6 (0.49) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL20864231 | 0.78 | CYP2A6 (0.49) | ERCC5CYP2A6MTORDRD2DRD4 | |
| SCHEMBL28195223 | 0.78 | CYP2A6 (0.49) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL31517290 | 0.78 | MAPT (0.49) | MAPTKDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2106213-B1 | SUBSTITUTED 1-(3-PYRIDINYL)PYRAZOL-4-YL-ACETIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDE AND PLANT GROWTH REGULATORS | BAYER IP GMBH (DE) | 2015-02-11 | — | — | EP | disclosed |
| CN-101583276-B | Substituted 1- (3-pyridyl) -pyrazol-4-yl acetic acids, method for the production thereof, and use thereof as herbicides and plant growth regulators | BAYER CROPSCIENCE AG | 2013-08-28 | — | — | CN | disclosed |
| US-8252723-B2 | Substituted 1-(3-pyridinyl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8067611-B2 | Substituted 1-(thiazolyl)-and 1-(isothiazolyl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20110257014-A1 | 1-(Heteroaryl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2011-10-20 | — | — | US | disclosed |
| US-20100197501-A1 | SUBSTITUTED 1-(THIAZOLYL)-AND 1-(ISOTHIAZOLYL)PYRAZOL-4-YLACETIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | US | disclosed |
| CN-101583276-A | Substituted 1- (3-pyridyl) -pyrazol-4-yl acetic acids, method for the production thereof, and use thereof as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2009-11-18 | — | — | CN | disclosed |
| EP-2106213-A2 | SUBSTITUTED 1-(3-PYRIDINYL)PYRAZOLE-4-YL ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2009-10-07 | — | — | EP | disclosed |
| US-20090036310-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-ylacetic Acids, Processes for Their Preparation and Their Use as Herbicides and Plant Growth Regulators | BAYER CORPSCIENCE GMBH (DE) | 2009-02-05 | — | — | US | disclosed |
| WO-2008080504-A3 | SUBSTITUTED 1-(3-PYRIDINYL)PYRAZOLE-4-YL ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008080504-A2 | SUBSTITUTED 1-(3-PYRIDINYL)PYRAZOLE-4-YL ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2008-07-10 | — | — | WO | disclosed |
| EP-1938686-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-yl-acetic acids, process for their preparation and their use as herbicide and plant growth regulator. | Bayer CropScience AG (DE) | 2008-07-02 | — | — | EP | disclosed |
| EP-1938686-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-yl-acetic acids, process for their preparation and their use as herbicide and plant growth regulator. | Bayer CropScience AG (DE) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036310-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-ylacetic Acids, Processes for Their Preparation and Their Use as Herbicides and Plant Growth Regulators | DDT, DDC, HPD | NAPRT 1931/4885MAPT 4484/4885KDM4E 224/4885 |
| US-20100197501-A1 | SUBSTITUTED 1-(THIAZOLYL)-AND 1-(ISOTHIAZOLYL)PYRAZOL-4-YLACETIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | THRA, TSHR, DDT | NAPRT 2564/4885MAPT 4674/4885KDM4E 2158/4885 |
| US-20110257014-A1 | 1-(Heteroaryl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | DDT, HPD, DDC | NAPRT 2358/4885MAPT 4198/4885KDM4E 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.