Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724513 | 0.92 | CYP3A4 (0.46) | CYP3A4KMT2AMEN1GAAKDM4E | |
| SCHEMBL6927455 | 0.88 | TAAR1 (0.39) | CYP3A4KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL12515330 | 0.87 | CYP3A4 (0.52) | CYP3A4KMT2AMEN1GAAKDM4E | |
| SCHEMBL3651991 | 0.85 | CYP3A4 (0.61) | CYP3A4KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8902778 | 0.85 | CYP3A4 (0.54) | CYP3A4KMT2AMEN1GAAKDM4E | |
| SCHEMBL12444082 | 0.84 | CYP3A4 (0.41) | CYP3A4KMT2AMEN1GAAKDM4E | |
| SCHEMBL13596339 | 0.83 | RAB9A (0.39) | CYP3A4KMT2AMEN1GAAKDM4E | |
| SCHEMBL13596372 | 0.82 | ALDH1A1 (0.56) | CYP3A4KMT2AKDM4ENPSR1ALDH1A1 | |
| SCHEMBL9417797 | 0.82 | CYP3A4 (0.52) | CYP3A4KMT2AMEN1KDM4EHDAC3 | |
| SCHEMBL11807436 | 0.81 | GAA (0.47) | CYP3A4KMT2AMEN1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420821-B2 | Process for production of 4-oxoquinoline compound | JAPAN TOBACCO INC. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | CYP4X1, CYP3A4, CYP3A7 | CYP3A4 2/4885KMT2A 975/4885MEN1 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.