Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704966 | 0.92 | LCK (0.60) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL2139729 | 0.88 | LCK (0.50) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL12444067 | 0.87 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL29765241 | 0.85 | LCK (0.73) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL347214 | 0.85 | LCK (0.73) | ALDH1A1KDM4EHPGDLCKFYN | |
| Hydrochloric Acid SCHEMBL28599506 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL2830233 | 0.84 | LCK (0.72) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL27476490 | 0.84 | HTT (0.53) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL22691985 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDLCKFYN | |
| SCHEMBL22116610 | 0.84 | LCK (0.67) | ALDH1A1KDM4EHPGDLCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107667088-B | Novel benzoic acid amide compound | 株式会社爱茉莉太平洋 | 2020-04-24 | — | — | CN | disclosed |
| EP-3279184-B1 | NOVEL BENZOIC ACID AMIDE COMPOUND | AMOREPACIFIC CORP (KR) | 2019-10-09 | — | — | EP | disclosed |
| US-10385011-B2 | Benzoic acid amide compound | AMOREPACIFIC CORPORATION (KR) | 2019-08-20 | — | — | US | disclosed |
| US-20180065922-A1 | NOVEL BENZOIC ACID AMIDE COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2018-03-08 | — | — | US | disclosed |
| EP-3279184-A1 | NOVEL BENZOIC ACID AMIDE COMPOUND | Amorepacific Corporation (KR) | 2018-02-07 | — | — | EP | disclosed |
| CN-107667088-A | NOVEL BENZOIC ACID AMIDE COMPOUND | 株式会社爱茉莉太平洋 | 2018-02-06 | — | — | CN | disclosed |
| US-20150299104-A1 | METHOD FOR PRODUCING 4-OXOQUINOLINE COMPOUND | JAPAN TOBACCO INC (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20130310595-A1 | Method for Producing 4-Oxoquinoline Compound | JAPAN TOBACCO INC. (JP) | 2013-11-21 | — | — | US | disclosed |
| US-8420821-B2 | Process for production of 4-oxoquinoline compound | JAPAN TOBACCO INC. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8383819-B2 | Method for producing 4-oxoquinoline compound | JAPAN TOBACCO INC. (JP) | 2013-02-26 | — | — | US | disclosed |
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090036684-A1 | METHOD FOR PRODUCING 4-OXOQUINOLINE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-7429616-B2 | Synthesis and complete stereochemical assignment of psymberin/irciniastatin for use as antitumor compounds | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2008-09-30 | — | — | US | disclosed |
| WO-2007011629-A2 | SYNTHESIS AND COMPLETE STEREOCHEMICAL ASSIGNMENT OF PSYMBERIN/IRCINIASTATIN FOR ANTI-TUMOR USE | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2007-01-25 | — | — | WO | disclosed |
| US-20070015821-A1 | Synthesis and complete stereochemical assignment of psymberin/irciniastatin for use as antitumor compounds | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM | 2007-01-18 | — | — | US | disclosed |
| US-20070015821-A1 | Synthesis and complete stereochemical assignment of psymberin/irciniastatin for use as antitumor compounds | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065922-A1 | NOVEL BENZOIC ACID AMIDE COMPOUND | TYR, MITF, NAT1 | ALDH1A1 176/4885KDM4E 799/4885HPGD 632/4885 |
| US-20150299104-A1 | METHOD FOR PRODUCING 4-OXOQUINOLINE COMPOUND | IMPDH1, IMPDH2, CDK20 | ALDH1A1 2769/4885KDM4E 780/4885HPGD 2058/4885 |
| US-20130310595-A1 | Method for Producing 4-Oxoquinoline Compound | IMPDH1, IMPDH2, CDK20 | ALDH1A1 2769/4885KDM4E 780/4885HPGD 2058/4885 |
| US-20070015821-A1 | Synthesis and complete stereochemical assignment of psymberin/irciniastatin for use as antitumor compounds | HCCS, RPS24, RPS27 | ALDH1A1 3015/4885KDM4E 4248/4885HPGD 1564/4885 |
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | CYP4X1, CYP3A4, CYP3A7 | ALDH1A1 1354/4885KDM4E 645/4885HPGD 1336/4885 |
| US-10385011-B2 | Benzoic acid amide compound | TYR, MITF, NAT1 | ALDH1A1 201/4885KDM4E 796/4885HPGD 571/4885 |
| US-20090036684-A1 | METHOD FOR PRODUCING 4-OXOQUINOLINE COMPOUND | IMPDH1, IMPDH2, CDK20 | ALDH1A1 2769/4885KDM4E 780/4885HPGD 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.