Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19266930 | 0.85 | MGLL (0.59) | MGLLALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL20730015 | 0.81 | MGLL (0.62) | MGLLALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL13535134 | 0.81 | ACHE (0.44) | ALDH1A1HIF1ATP53MEN1KMT2A | |
| SCHEMBL21648873 | 0.79 | MGLL (0.51) | MGLLALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL21648768 | 0.78 | MGLL (0.57) | MGLLALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL17696612 | 0.76 | MGLL (0.69) | MGLLALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL4141287 | 0.75 | MGLL (0.47) | MGLLALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL12286751 | 0.75 | MGLL (0.71) | MGLLALDH1A1HPGDBLMGSK3A | |
| SCHEMBL193799 | 0.75 | MGLL (0.71) | MGLLALDH1A1HPGDBLMGSK3A | |
| SCHEMBL13695959 | 0.75 | MGLL (0.71) | MGLLALDH1A1HPGDBLMGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4362982-A1 | CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY | Byondis B.V. (NL) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023275025-A1 | CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY | BYONDIS B.V. (NL) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023275025-A1 | CONJUGATES COMPRISING PHOSPHOANTIGENS AND THEIR USE IN THERAPY | BYONDIS B.V. (NL) | 2023-01-05 | — | — | WO | disclosed |
| EP-1994000-B1 | WATER-SOLUBLE CC-1065 ANALOGS AND THEIR CONJUGATES | SYNTARGA BV (NL) | 2017-08-23 | — | — | EP | disclosed |
| US-8940784-B2 | Water-soluble CC-1065 analogs and their conjugates | SYNTARGA B.V. (NL) | 2015-01-27 | — | — | US | disclosed |
| US-20090318668-A1 | Water-Soluble CC-1065 Analogs and Their Conjugates | Georg-August-Universität Göttingen Stiftung öffentlichen Rechts (ohne Bereich Humanmedizin) (DE) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318668-A1 | Water-Soluble CC-1065 Analogs and Their Conjugates | PCNA, DCK, BAD | MGLL 4666/4885ALDH1A1 2365/4885HPGD 2747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.