Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021350 | 0.89 | ALDH1A1 (0.78) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL6554287 | 0.83 | IDO1 (0.52) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL1788919 | 0.83 | KDM4E (0.53) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL1788921 | 0.81 | NR4A2 (0.53) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL137476 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL12992908 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7303745 | 0.80 | HRH3 (0.46) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL3936532 | 0.80 | LMNA (0.43) | ALDH1A1KDM4ELMNA | |
| SCHEMBL6556972 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL11571335 | 0.79 | ALDH1A1 (0.64) | ALDH1A1IDO1MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250387403-A1 | SELECTIVE SIGMA-2 RECEPTOR LIGANDS AS MODULATORS OF TMEM97 | UNIV TEXAS (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4525879-A2 | SELECTIVE SIGMA-2 RECEPTOR LIGANDS AS MODULATORS OF TMEM97 | Board of Regents, The University of Texas System (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-117164462-B | Diaryl methane compound and preparation method and application thereof | 江西师范大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-117164462-A | Diaryl methane compound and preparation method and application thereof | 江西师范大学 | 2023-12-05 | — | — | CN | disclosed |
| WO-2023225563-A2 | SELECTIVE SIGMA-2 RECEPTOR LIGANDS AS MODULATORS OF TMEM97 | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-11-23 | — | — | WO | disclosed |
| CN-108779096-B | Fluorine-substituted cyclopropylamine compounds, and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-07-01 | — | — | CN | disclosed |
| US-10836743-B2 | Fluorinated cyclopropylamine compound, preparation method therefor, pharmaceutical composition thereof, and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-11-17 | — | — | US | disclosed |
| EP-3486231-B1 | PYRROLIDINE DERIVATIVE SERVING AS PPAR AGONIST | GUANGDONG RAYNOVENT BIOTECH CO LTD (CN) | 2020-05-20 | — | — | EP | disclosed |
| US-20190225597-A1 | PYRROLIDINE DERIVATIVES AS PPAR AGONISTS | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2019-07-25 | — | — | US | disclosed |
| EP-3486231-A1 | PYRROLIDINE DERIVATIVE SERVING AS PPAR AGONIST | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2019-05-22 | — | — | EP | disclosed |
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |
| US-5436242-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation | SANKYO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |
| US-5288726-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | UBE INDUSTRIES LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| US-5254558-A | Substituted 1,3-diazines as leukocyte elastase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-19 | — | — | US | disclosed |
| EP-0542411-A2 | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | Sankyo Company Limited (JP) | 1993-05-19 | — | — | EP | disclosed |
| EP-0237522-B1 | PHARMACEUTICALLY ACTIVE DERIVATIVES OF TRYPTOPHAN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1993-02-24 | — | — | EP | disclosed |
| EP-0528633-A1 | Pyrimidinyl acetamides as elastase inhibitors | ZENECA LIMITED (GB) | 1993-02-24 | — | — | EP | disclosed |
| US-4870097-A | ANALGESICS, CENTRAL NERVOUS SYSTEM DISORDERS | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1989-09-26 | — | — | US | disclosed |
| EP-0237522-A1 | PHARMACEUTICALLY ACTIVE DERIVATIVES OF TRYPTOPHAN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | ROTTA RESEARCH LAB (IT) | 1987-09-23 | — | — | EP | disclosed |
| WO-1986003489-A1 | PHARMACEUTICALLY ACTIVE DERIVATIVES OF TRYPTOPHAN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1986-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250387403-A1 | SELECTIVE SIGMA-2 RECEPTOR LIGANDS AS MODULATORS OF TMEM97 | TMEM97, SIGMAR1, OPRL1 | ALDH1A1 1645/4885MMP1 4774/4885MMP2 4723/4885 |
| US-20190225597-A1 | PYRROLIDINE DERIVATIVES AS PPAR AGONISTS | PPARD, PPARA, PPARG | ALDH1A1 1866/4885MMP1 741/4885MMP2 2595/4885 |
| US-10836743-B2 | Fluorinated cyclopropylamine compound, preparation method therefor, pharmaceutical composition thereof, and uses thereof | SETDB1, KDM1B, SETD7 | ALDH1A1 354/4885MMP1 3456/4885MMP2 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.