Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000756 | 0.82 | HSD11B1 (0.46) | HSD11B1ALDH1A1POLBTDP1L3MBTL1 | |
| Lithium SCHEMBL5691154 | 0.79 | HSD11B1 (0.44) | HSD11B1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL30863576 | 0.77 | ALDH1A1 (0.43) | HSD11B1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL728455 | 0.77 | ALDH1A1 (0.43) | HSD11B1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL13601605 | 0.76 | MPL (0.40) | HSD11B1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL14435315 | 0.76 | TRPA1 (0.35) | P2RX7CES1 | |
| Water SCHEMBL27581485 | 0.75 | ALDH1A1 (0.41) | HSD11B1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL6067687 | 0.75 | HSD11B1 (0.55) | HSD11B1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL20150821 | 0.74 | AR (0.36) | HSD11B1ALDH1A1CA2PDK2HTT | |
| SCHEMBL23324839 | 0.74 | CA2 (0.39) | ALDH1A1POLBTDP1L3MBTL1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094390-B | Method for producing polyols | 陶氏环球技术有限责任公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-111263785-B | Lewis acid polymerization catalyst | 陶氏环球技术有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-111263784-B | Method for producing polyols | 陶氏环球技术有限责任公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2020130143-A1 | DENTAL ADHESIVE COMPOSITION | クラレノリタケデンタル株式会社 | 2020-06-25 | — | — | WO | disclosed |
| CN-111263785-A | Lewis acid polymerization catalysts | 陶氏环球技术有限责任公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-111263784-A | Process for producing polyol | 陶氏环球技术有限责任公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-111094390-A | Process for producing polyol | 陶氏环球技术有限责任公司 | 2020-05-01 | — | — | CN | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | HSD11B1 2424/4885ALDH1A1 2990/4885POLB 4519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.