Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 4/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14089991 | 0.88 | RXRA (0.54) | CSNK2A2CSNK2BRXRARXRBRXRG | |
| SCHEMBL14089937 | 0.83 | CSNK2A2 (0.49) | S1PR1CSNK2A2CSNK2BRXRARXRB | |
| SCHEMBL2773780 | 0.82 | AKR1C3 (0.62) | RXRAALDH1A1AKR1C3AKR1C2FABP4 | |
| SCHEMBL2590647 | 0.81 | RAB9A (0.49) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL14213194 | 0.80 | RXRA (0.49) | CSNK2A2CSNK2BRXRARXRBRXRG | |
| SCHEMBL14089990 | 0.79 | PTGER1 (0.49) | CSNK2A2CSNK2BRXRARXRBRXRG | |
| SCHEMBL272092 | 0.78 | TTR (0.56) | ALDH1A1L3MBTL1TTR | |
| SCHEMBL13601645 | 0.78 | FABP4 (0.52) | S1PR1RORCSCN9ASCN10AALDH1A1 | |
| SCHEMBL319915 | 0.78 | RORC (0.52) | S1PR1RORCALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL536004 | 0.78 | FFAR4 (0.59) | CSNK2A2CSNK2BRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | S1PR1 1/4885CSNK2A2 2875/4885CSNK2B 3290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.