Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 3/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601631 | 0.87 | LDHA (0.49) | DHODHNOTUMSCN9AACMSDMEN1 | |
| SCHEMBL13601882 | 0.81 | TUBB4A (0.48) | DCLRE1BGPR35DHODHNR4A1NR4A2 | |
| SCHEMBL2429144 | 0.81 | LDHA (0.49) | DHODHNOTUMACMSDMEN1LMNA | |
| SCHEMBL17797026 | 0.80 | HDAC7 (0.51) | DCLRE1BGPR35DHODHNOTUMNR4A1 | |
| SCHEMBL27456537 | 0.80 | GPR35 (0.49) | DCLRE1BGPR35DHODHNOTUMNR4A1 | |
| SCHEMBL31397801 | 0.79 | HTT (0.59) | DCLRE1BGPR35DHODHNR4A1NR4A2 | |
| SCHEMBL269851 | 0.79 | HTT (0.59) | DCLRE1BGPR35DHODHNR4A1NR4A2 | |
| SCHEMBL17797037 | 0.79 | DCLRE1B (0.56) | DCLRE1BGPR35DHODHNR4A1NR4A2 | |
| SCHEMBL4539558 | 0.77 | AKR1C3 (0.55) | DCLRE1BNR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL1890376 | 0.77 | GRIK1 (0.52) | DCLRE1BNR4A1NR4A2NR4A3KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | DCLRE1B 1678/4885GPR35 134/4885DHODH 2603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.