Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 3/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.43 |
| ▸ | PPM1G | O15355 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601648 | 0.89 | TTR (0.44) | TTRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL13652585 | 0.88 | TTR (0.48) | TTRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL4502244 | 0.86 | KMO (0.47) | TTRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL272092 | 0.84 | TTR (0.56) | TTRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL13601655 | 0.84 | HTT (0.51) | TTRMRGPRX4AKR1C3AKR1C2 | |
| SCHEMBL13601649 | 0.84 | RORC (0.49) | TTRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL68014 | 0.82 | ALDH1A1 (0.57) | TTRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL12388484 | 0.82 | TTR (0.50) | TTRKDM4EALDH1A1GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4352471 | 0.80 | ALDH1A1 (0.56) | TTRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL3558703 | 0.80 | MYC (0.58) | TTRKDM4EALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| WO-2009131090-A1 | AMINO ACID COMPOUND | 旭化成ファーマ株式会社 (JP) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | TTR 2102/4885KDM4E 3224/4885ALDH1A1 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.