Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.39 |
| ▸ | PPM1G | O15355 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601671 | 0.85 | RORC (0.47) | KDM4EALDH1A1GAAL3MBTL1RORC | |
| SCHEMBL4517114 | 0.85 | SCN9A (0.43) | KDM4EALDH1A1GAAL3MBTL1RORC | |
| SCHEMBL4517107 | 0.84 | RORC (0.42) | KDM4EALDH1A1GAAL3MBTL1RORC | |
| SCHEMBL13601705 | 0.84 | AKR1C3 (0.40) | KDM4EALDH1A1GAAL3MBTL1RORC | |
| SCHEMBL319915 | 0.77 | RORC (0.52) | ALDH1A1RORCTTRPTPN7PPM1G | |
| SCHEMBL13601649 | 0.77 | RORC (0.49) | KDM4EALDH1A1GAAL3MBTL1RORC | |
| SCHEMBL68014 | 0.75 | ALDH1A1 (0.57) | KDM4EALDH1A1GAAL3MBTL1TTR | |
| SCHEMBL272092 | 0.74 | TTR (0.56) | KDM4EALDH1A1GAAL3MBTL1TTR | |
| SCHEMBL13601653 | 0.74 | TTR (0.45) | KDM4EALDH1A1GAAL3MBTL1TTR | |
| Hydrochloric Acid SCHEMBL4352471 | 0.74 | ALDH1A1 (0.56) | KDM4EALDH1A1GAAL3MBTL1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | KDM4E 3224/4885ALDH1A1 2990/4885GAA 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.