Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3098557 | 1.00 | L3MBTL1 (0.45) | L3MBTL1TP53BP1L3MBTL3SLC6A12FAAH | |
| SCHEMBL13157799 | 1.00 | L3MBTL1 (0.45) | L3MBTL1TP53BP1L3MBTL3SLC6A12FAAH | |
| SCHEMBL13157813 | 0.96 | TP53BP1 (0.39) | L3MBTL1TP53BP1L3MBTL3FAAHTP53 | |
| SCHEMBL3107837 | 0.96 | TP53BP1 (0.39) | L3MBTL1TP53BP1L3MBTL3FAAHTP53 | |
| SCHEMBL3100379 | 0.89 | TP53BP1 (0.54) | L3MBTL1TP53BP1L3MBTL3MAPK8MAPK10 | |
| SCHEMBL13157797 | 0.89 | TP53BP1 (0.54) | L3MBTL1TP53BP1L3MBTL3MAPK8MAPK10 | |
| SCHEMBL13604130 | 0.89 | TP53BP1 (0.54) | L3MBTL1TP53BP1L3MBTL3MAPK8MAPK10 | |
| SCHEMBL13157832 | 0.88 | FAAH (0.47) | L3MBTL1TP53BP1L3MBTL3SLC6A12FAAH | |
| SCHEMBL3099993 | 0.88 | FAAH (0.47) | L3MBTL1TP53BP1L3MBTL3SLC6A12FAAH | |
| SCHEMBL13157819 | 0.87 | F10 (0.44) | SLC6A12FAAHSMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399455-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399455-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-7635698-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-12-22 | — | — | US | disclosed |
| US-7635698-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-12-22 | — | — | US | disclosed |