Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 14/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 10/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | CDKL3 | Q8IVW4 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604130 | 1.00 | TP53BP1 (0.54) | TP53BP1L3MBTL3L3MBTL1MAPK10MAPK8 | |
| SCHEMBL13157797 | 1.00 | TP53BP1 (0.54) | TP53BP1L3MBTL3L3MBTL1MAPK10MAPK8 | |
| SCHEMBL3093041 | 0.95 | L3MBTL1 (0.47) | TP53BP1L3MBTL3L3MBTL1MAPK10MAPK8 | |
| SCHEMBL13157806 | 0.95 | L3MBTL1 (0.47) | TP53BP1L3MBTL3L3MBTL1MAPK10MAPK8 | |
| SCHEMBL13604134 | 0.95 | L3MBTL1 (0.47) | TP53BP1L3MBTL3L3MBTL1MAPK10MAPK8 | |
| SCHEMBL13604133 | 0.89 | L3MBTL1 (0.45) | TP53BP1L3MBTL3L3MBTL1MAPK10MAPK8 | |
| SCHEMBL13157799 | 0.89 | L3MBTL1 (0.45) | TP53BP1L3MBTL3L3MBTL1MAPK10MAPK8 | |
| SCHEMBL3098557 | 0.89 | L3MBTL1 (0.45) | TP53BP1L3MBTL3L3MBTL1MAPK10MAPK8 | |
| SCHEMBL13157828 | 0.86 | TP53BP1 (0.52) | TP53BP1L3MBTL3L3MBTL1SLC18A3CYP2C9 | |
| SCHEMBL3107714 | 0.86 | TP53BP1 (0.52) | TP53BP1L3MBTL3L3MBTL1SLC18A3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399455-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | ACKR3, CCR5, CXCR2 | TP53BP1 3833/4885L3MBTL3 4678/4885L3MBTL1 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.