Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604133 | 1.00 | L3MBTL1 (0.45) | L3MBTL1TP53BP1L3MBTL3SLC6A12FAAH | |
| SCHEMBL13157799 | 1.00 | L3MBTL1 (0.45) | L3MBTL1TP53BP1L3MBTL3SLC6A12FAAH | |
| SCHEMBL13157813 | 0.96 | TP53BP1 (0.39) | L3MBTL1TP53BP1L3MBTL3FAAHTP53 | |
| SCHEMBL3107837 | 0.96 | TP53BP1 (0.39) | L3MBTL1TP53BP1L3MBTL3FAAHTP53 | |
| SCHEMBL3100379 | 0.89 | TP53BP1 (0.54) | L3MBTL1TP53BP1L3MBTL3MAPK8MAPK10 | |
| SCHEMBL13157797 | 0.89 | TP53BP1 (0.54) | L3MBTL1TP53BP1L3MBTL3MAPK8MAPK10 | |
| SCHEMBL13604130 | 0.89 | TP53BP1 (0.54) | L3MBTL1TP53BP1L3MBTL3MAPK8MAPK10 | |
| SCHEMBL13157832 | 0.88 | FAAH (0.47) | L3MBTL1TP53BP1L3MBTL3SLC6A12FAAH | |
| SCHEMBL3099993 | 0.88 | FAAH (0.47) | L3MBTL1TP53BP1L3MBTL3SLC6A12FAAH | |
| SCHEMBL13157819 | 0.87 | F10 (0.44) | SLC6A12FAAHSMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399455-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | ACKR3, CCR5, CXCR2 | L3MBTL1 4317/4885TP53BP1 3833/4885L3MBTL3 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.