Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604229 | 0.82 | LOXL2 (0.49) | ALDH1A1MEN1KMT2ALOXL2CYP1A2 | |
| SCHEMBL10360804 | 0.82 | ALDH1A1 (0.77) | ALDH1A1LMNAKDM4EKMT2APOLB | |
| SCHEMBL1347417 | 0.81 | KMT2A (0.48) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL827693 | 0.81 | PSMD14 (0.57) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL4059940 | 0.78 | KDM4E (0.50) | ALDH1A1KDM4ELOXL2CYP1A2MTNR1A | |
| SCHEMBL827213 | 0.76 | KDM4E (0.59) | KDM4EMEN1KMT2AMAPK8MAPK9 | |
| SCHEMBL993441 | 0.75 | ALDH1A1 (0.59) | ALDH1A1LMNAKDM4EKMT2APOLB | |
| SCHEMBL29396988 | 0.75 | KDM4E (0.54) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL15452580 | 0.75 | KDM4E (0.54) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL7824800 | 0.75 | MAPT (0.49) | ALDH1A1LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128156-A1 | NOVEL OXADIAZOLE DERIVATIVES AND THIADIAZOLE DERIVATIVES HAVING NEOVASCULARIZATION INHIBITING ACTIVITY | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-02 | — | — | EP | disclosed |