Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604226 | 0.82 | ALDH1A1 (0.55) | LOXL2NSD2FLT1KDRCYP1A2 | |
| SCHEMBL5603305 | 0.82 | NSD2 (0.56) | LOXL2NSD2P2RX7ALDH1A1HDAC3 | |
| SCHEMBL1346778 | 0.80 | MEN1 (0.50) | LOXL2NSD2CYP1A2ALDH1A1MEN1 | |
| SCHEMBL16572948 | 0.77 | NSD2 (0.67) | NSD2P2RX7ALDH1A1MEN1KMT2A | |
| Biphenyl SCHEMBL27669532 | 0.77 | NSD2 (0.55) | LOXL2NSD2CYP1A2ALDH1A1HDAC3 | |
| SCHEMBL13604312 | 0.75 | KDR (0.64) | KDRCYP1A2P2RX7ALDH1A1ADRB2 | |
| SCHEMBL22994602 | 0.73 | ALDH1A1 (0.71) | KDRALDH1A1KMT2AADRB2HDAC1 | |
| SCHEMBL3412935 | 0.72 | GAA (0.62) | P2RX7ALDH1A1MEN1KMT2AADRB2 | |
| SCHEMBL1650885 | 0.72 | CYP1A2 (0.55) | LOXL2FLT1KDRCYP1A2ALDH1A1 | |
| SCHEMBL30286812 | 0.72 | CTSD (0.51) | KDRCYP1A2P2RX7ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128156-A1 | NOVEL OXADIAZOLE DERIVATIVES AND THIADIAZOLE DERIVATIVES HAVING NEOVASCULARIZATION INHIBITING ACTIVITY | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-02 | — | — | EP | disclosed |