Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 6/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13606745 | 0.92 | MAPT (0.40) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL14277940 | 0.83 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL13606747 | 0.82 | MAPT (0.42) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL17041223 | 0.81 | NPC1 (0.40) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL10101784 | 0.80 | MAOA (0.45) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL12609448 | 0.79 | L3MBTL1 (0.74) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL13606751 | 0.77 | MAPT (0.39) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL13606786 | 0.77 | MAPT (0.39) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL13606743 | 0.77 | MAPT (0.45) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL10101787 | 0.76 | MAOA (0.42) | ALDH1A1L3MBTL1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298898-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090298898-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-7569727-B2 | N-{(4-{3-[2,6-dichloro-4-(3,3-dichloro-allyloxy)-phenoxy]-propoxy}-phenyl)-[(E)-ethoxyimino]-methyl}-2,2,2-trifluoroacetamide; exhibit valuable preventive and/or curative activity even at low rates of concentration, while being well tolerated by warm-blooded animals, fish and plants | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-7569727-B2 | N-{(4-{3-[2,6-dichloro-4-(3,3-dichloro-allyloxy)-phenoxy]-propoxy}-phenyl)-[(E)-ethoxyimino]-methyl}-2,2,2-trifluoroacetamide; exhibit valuable preventive and/or curative activity even at low rates of concentration, while being well tolerated by warm-blooded animals, fish and plants | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| EP-2080752-A1 | Pesticidally active ketone and oxime derivatives | Syngenta Participations AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| US-20080200525-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-20080200525-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298898-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | CHRM2, FOXO3, CHRM1 | ALDH1A1 1934/4885L3MBTL1 469/4885KMT2A 2123/4885 |
| US-20080200525-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | CHRM2, FOXO3, CHRM1 | ALDH1A1 1934/4885L3MBTL1 469/4885KMT2A 2123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.