Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2978236 | 0.84 | XDH (0.32) | XDH | |
| SCHEMBL13609903 | 0.84 | — | — | |
| SCHEMBL2659824 | 0.69 | FBP1 (0.56) | XDHALDH1A1 | |
| SCHEMBL27784596 | 0.67 | XDH (0.38) | XDHALDH1A1HTT | |
| SCHEMBL2668864 | 0.67 | — | — | |
| SCHEMBL13222113 | 0.67 | — | — | |
| SCHEMBL2660430 | 0.66 | XDH (0.53) | XDHALDH1A1HTT | |
| SCHEMBL1663359 | 0.65 | MAPT (0.55) | ALDH1A1HTT | |
| SCHEMBL8495069 | 0.64 | ALDH1A1 (0.53) | ALDH1A1HTT | |
| SCHEMBL13622820 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286975-A1 | Indole compound | YASUMA TSUNEO | 2009-11-19 | — | — | US | disclosed |
| US-20090286975-A1 | Indole compound | YASUMA TSUNEO | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286975-A1 | Indole compound | GCKR, GPR119, SLC5A1 | XDH 1286/4885ALDH1A1 376/4885HTT 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.