Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.74 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360540 | 0.93 | LMNA (0.76) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL1360597 | 0.92 | LMNA (0.74) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL681514 | 0.92 | LMNA (0.84) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL1360983 | 0.90 | LMNA (0.71) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL1360996 | 0.90 | LMNA (0.60) | LMNACYP2C19HIF1A | |
| SCHEMBL682143 | 0.89 | LMNA (0.80) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL12855756 | 0.89 | LMNA (0.84) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL12855754 | 0.87 | LMNA (0.84) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL10058205 | 0.87 | LMNA (0.76) | LMNACYP2C19HIF1AEGFRSRC | |
| Iopentol SCHEMBL24471 | 0.86 | LMNA (0.82) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989178-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2012-10-31 | — | — | EP | claimed |
| US-8067637-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2011-11-29 | — | — | US | claimed |
| US-20090028799-A1 | CONTRAST AGENTS | PRIEBE HANNO | 2009-01-29 | — | — | US | claimed |
| EP-1989178-A1 | CONTRAST AGENTS | GE Healthcare AS (NO) | 2008-11-12 | — | — | EP | claimed |
| WO-2007094677-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2007-08-23 | — | — | WO | claimed |
| EP-1989178-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2012-10-31 | — | — | EP | disclosed |
| EP-1989178-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2012-10-31 | — | — | EP | disclosed |
| US-8067637-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2011-11-29 | — | — | US | disclosed |
| US-8067637-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2011-11-29 | — | — | US | disclosed |
| US-8067637-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2011-11-29 | — | — | US | disclosed |
| US-20090028799-A1 | CONTRAST AGENTS | PRIEBE HANNO | 2009-01-29 | — | — | US | disclosed |
| US-20090028799-A1 | CONTRAST AGENTS | PRIEBE HANNO | 2009-01-29 | — | — | US | disclosed |
| US-20090028799-A1 | CONTRAST AGENTS | PRIEBE HANNO | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090028799-A1 | CONTRAST AGENTS | IPO4, SLCO1B3, SLCO4C1 | LMNA 1634/4885CYP2C19 3822/4885HIF1A 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.