Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855756 | 0.98 | LMNA (0.84) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL681514 | 0.95 | LMNA (0.84) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL10058205 | 0.93 | LMNA (0.76) | LMNACYP2C19HIF1AEGFRSRC | |
| Iodixanol SCHEMBL21546 | 0.92 | LMNA (1.00) | LMNACYP2C19HIF1AEGFRSRC | |
| Iodixanol SCHEMBL37712 | 0.92 | LMNA (1.00) | LMNACYP2C19HIF1AEGFRSRC | |
| Iodixanol SCHEMBL8845042 | 0.92 | LMNA (1.00) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL682143 | 0.91 | LMNA (0.80) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL12855752 | 0.91 | LMNA (0.84) | LMNACYP2C19HIF1AEGFRSRC | |
| Iodixanol SCHEMBL22645199 | 0.91 | LMNA (0.97) | LMNACYP2C19HIF1AEGFRSRC | |
| Iohexol SCHEMBL31722694 | 0.90 | CYP2C19 (1.00) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239857-A | Preparation method of iodixanol impurity I | 浙江海洲制药股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| US-8969619-B2 | Synthesis of iodixanol in propyleneglycol | GE HEALTHCARE AS (NO) | 2015-03-03 | — | — | US | disclosed |
| US-8969619-B2 | Synthesis of iodixanol in propyleneglycol | GE HEALTHCARE AS (NO) | 2015-03-03 | — | — | US | disclosed |
| US-8962886-B2 | Synthesis of iodixanol in methanol | GE HEALTHCARE AS (NO) | 2015-02-24 | — | — | US | disclosed |
| US-8962886-B2 | Synthesis of iodixanol in methanol | GE HEALTHCARE AS (NO) | 2015-02-24 | — | — | US | disclosed |
| US-8962887-B2 | Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol | GE HEALTHCARE AS (NO) | 2015-02-24 | — | — | US | disclosed |
| US-8962887-B2 | Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol | GE HEALTHCARE AS (NO) | 2015-02-24 | — | — | US | disclosed |
| EP-2279998-A1 | Synthesis of iodixanol in propyleneglycol | GE Healthcare AS (NO) | 2011-02-02 | — | — | EP | disclosed |
| US-20110021832-A1 | SYNTHESIS OF IODIXANOL IN WATER | GE HEALTHCARE AS (NO) | 2011-01-27 | — | — | US | disclosed |
| US-20110021831-A1 | SYTNHESIS OF IODIXANOL IN 1-METHOXY-2-PROPANOL AND WATER OR METHANOL | GE HEALTHCARE AS (NO) | 2011-01-27 | — | — | US | disclosed |
| US-20110021831-A1 | SYTNHESIS OF IODIXANOL IN 1-METHOXY-2-PROPANOL AND WATER OR METHANOL | GE HEALTHCARE AS (NO) | 2011-01-27 | — | — | US | disclosed |
| US-20110021830-A1 | SYTNHESIS OF IODIXANOL IN PROPYLENEGLYCOL | GE HEALTHCARE AS (NO) | 2011-01-27 | — | — | US | disclosed |
| US-20110021829-A1 | SYTNHESIS OF IODIXANOL IN METHANOL | GE HEALTHCARE AS (NO) | 2011-01-27 | — | — | US | disclosed |
| US-20110021829-A1 | SYTNHESIS OF IODIXANOL IN METHANOL | GE HEALTHCARE AS (NO) | 2011-01-27 | — | — | US | disclosed |
| US-20110021830-A1 | SYTNHESIS OF IODIXANOL IN PROPYLENEGLYCOL | GE HEALTHCARE AS (NO) | 2011-01-27 | — | — | US | disclosed |
| US-20110021832-A1 | SYNTHESIS OF IODIXANOL IN WATER | GE HEALTHCARE AS (NO) | 2011-01-27 | — | — | US | disclosed |
| EP-2277852-A1 | Synthesis of iodixanol in water | GE Healthcare AS (NO) | 2011-01-26 | — | — | EP | disclosed |
| EP-2277854-A1 | Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol | GE Healthcare AS (NO) | 2011-01-26 | — | — | EP | disclosed |
| EP-2277853-A1 | Synthesis of iodixanol in methanol | GE Healthcare AS (NO) | 2011-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021832-A1 | SYNTHESIS OF IODIXANOL IN WATER | AQP1, AQP3, HDHD5 | LMNA 3857/4885CYP2C19 2157/4885HIF1A 730/4885 |
| US-20110021830-A1 | SYTNHESIS OF IODIXANOL IN PROPYLENEGLYCOL | SYNGR2, SSTR2, SYPL1 | LMNA 1475/4885CYP2C19 2540/4885HIF1A 2536/4885 |
| US-20110021829-A1 | SYTNHESIS OF IODIXANOL IN METHANOL | DBH, CYTH2, SYNGR2 | LMNA 1469/4885CYP2C19 2658/4885HIF1A 1901/4885 |
| US-20110021831-A1 | SYTNHESIS OF IODIXANOL IN 1-METHOXY-2-PROPANOL AND WATER OR METHANOL | CYTH2, ANXA11, SYNGR2 | LMNA 715/4885CYP2C19 3065/4885HIF1A 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.