Iopentol

Iopentol

SCHEMBL24471

COCC(O)CN(C(C)=O)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.82
CYP2C19 P33261 1/20 0.82
HIF1A Q16665 1/20 0.82
EGFR P00533 1/20 0.33
SRC P12931 1/20 0.33
MAP2K1 Q02750 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iopentol SCHEMBL8845316 1.00 LMNA (0.82) LMNACYP2C19HIF1AEGFRSRC
Iopentol SCHEMBL14740647 0.99 CYP2C19 (0.84) LMNACYP2C19HIF1AEGFRSRC
Iodixanol SCHEMBL28086309 0.99 LMNA (0.84) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL10058205 0.96 LMNA (0.76) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL9564078 0.96 LMNA (0.76) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL682143 0.92 LMNA (0.80) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL681514 0.92 LMNA (0.84) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL3435296 0.92 LMNA (0.76) LMNACYP2C19HIF1AALDH1A1
Iodixanol SCHEMBL37712 0.91 LMNA (1.00) LMNACYP2C19HIF1AEGFRSRC
Iohexol SCHEMBL31722694 0.91 CYP2C19 (1.00) LMNACYP2C19HIF1AEGFRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2749 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101973-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-15 WO claimed
CN-122029126-A Method for obtaining iodide ions from a solution comprising an iodine-containing aromatic compound 伯拉考成像股份公司 2026-05-12 CN claimed
US-12616681-B2 Compositions and methods for treating renal injury CASE WESTERN RESERVE UNIVERSITY (US) 2026-05-05 US claimed
WO-2026090138-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 WO claimed
US-20260108635-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-23 US claimed
EP-4683579-A1 RELIEVE BACK PAIN AND/OR REBUILDING INTERVERTERAL DISC Yeung, Jeffrey E. (US) 2026-01-28 EP claimed
US-20250312400-A1 Intrathecal Delivery of Recombinant Adeno-Associated Virus Encoding Methyl-CPG Binding Protein 2 NATIONWIDE CHILDRENS HOSPITAL INC (US) 2025-10-09 US claimed
US-12404523-B2 Adeno-associated virus delivery of CLN3 polynucleotide RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) 2025-09-02 US claimed
US-12357663-B2 Intrathecal delivery of recombinant adeno-associated virus encoding methyl-CpG binding protein 2 NATIONWIDE CHILDREN'S HOSPITAL, INC. (US) 2025-07-15 US claimed
US-20250205368-A1 Intrathecal Delivery of Recombinant Adeno-Associated Virus 9 NATIONWIDE CHILDRENS HOSPITAL (US) 2025-06-26 US claimed
EP-0510086-A1 INTERDIGITATION-FUSION LIPOSOMES AND GELS. LIPOSOME CO INC (US) 1992-10-28 EP claimed
EP-0473729-A1 CONTRAST MEDIA NYCOMED AS (NO) 1992-03-11 EP claimed
EP-0463013-A1 CONTRAST MEDIA NYCOMED AS (NO) 1992-01-02 EP claimed
WO-1991012868-A1 REVERSED PHASE CHROMATOGRAPHIC PROCESS MALLINCKRODT, INC. (US) 1991-09-05 WO claimed
WO-1991010422-A1 INTERDIGITATION-FUSION LIPOSOMES AND GELS THE LIPOSOME COMPANY, INC. (US) 1991-07-25 WO claimed
EP-0414288-A1 Contrast media NYCOMED IMAGING AS (NO) 1991-02-27 EP claimed
WO-1991001149-A1 CONTRAST MEDIA NYCOMED AS (NO) 1991-02-07 WO claimed
WO-1990011094-A1 CONTRAST MEDIA NYCOMED AS (NO) 1990-10-04 WO claimed
EP-0390242-A1 Contrast media NYCOMED IMAGING AS (NO) 1990-10-03 EP claimed
CN-1045528-A CONTRAST MEDIA NYCOMED AS (NO) 1990-09-26 CN claimed