Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23478698 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TRPM5NAMPTFFAR1 | |
| SCHEMBL13610350 | 0.79 | TDP1 (0.41) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL13610284 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TRPM5NAMPTFFAR1 | |
| SCHEMBL13610439 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HSD17B10FFAR1PTK6KDM4E | |
| SCHEMBL13610430 | 0.77 | NAMPT (0.36) | ALDH1A1HSD17B10TRPM5NAMPT | |
| SCHEMBL13610429 | 0.76 | ALDH1A1 (0.37) | ALDH1A1HSD17B10FFAR1NPC1RAB9A | |
| SCHEMBL13610306 | 0.76 | L3MBTL1 (0.44) | ALDH1A1FFAR1PTK6NPC1RAB9A | |
| SCHEMBL29976332 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TRPM5NAMPTFFAR1 | |
| SCHEMBL9676880 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TRPM5NAMPTFFAR1 | |
| SCHEMBL13610431 | 0.75 | SMN1; SMN2 (0.40) | ALDH1A1HSD17B10NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622507-B2 | Substituted organosulfur compounds and methods of using thereof | ACEA BIOSCIENCES INC. (US) | 2009-11-24 | — | — | US | disclosed |