Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2620993 | 0.80 | NPC1 (0.47) | ALDH1A1HSD17B10TRPM5FFAR1PTK6 | |
| SCHEMBL13610446 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TRPM5FFAR1PTK6 | |
| SCHEMBL29976332 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TRPM5FFAR1PTK6 | |
| SCHEMBL9676880 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TRPM5FFAR1PTK6 | |
| SCHEMBL6647512 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TRPM5FFAR1PTK6 | |
| SCHEMBL3819546 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TRPM5FFAR1SMN1; SMN2 | |
| SCHEMBL9921443 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TRPM5FFAR1PTK6 | |
| SCHEMBL2357662 | 0.77 | HSD17B10 (0.50) | ALDH1A1HSD17B10TRPM5FFAR1SMN1; SMN2 | |
| SCHEMBL6396893 | 0.77 | CYP2A6 (0.47) | ALDH1A1HSD17B10TRPM5FFAR1SMN1; SMN2 | |
| SCHEMBL13610284 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TRPM5FFAR1PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807641-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| US-20210171531-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171531-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | ALDH1A1 4709/4885HSD17B10 3100/4885TRPM5 3761/4885 |
| US-11807641-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | ALDH1A1 4709/4885HSD17B10 3100/4885TRPM5 3761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.