Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040434 | 0.91 | DRD2 (0.63) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL7040433 | 0.91 | DRD2 (0.63) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL21593634 | 0.91 | DRD2 (0.63) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL692584 | 0.84 | CYP1A2 (0.70) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL692583 | 0.84 | CYP1A2 (0.70) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL13169532 | 0.83 | CYP1A2 (0.73) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL28456976 | 0.83 | CYP1A2 (0.73) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL28891768 | 0.83 | CYP1A2 (0.73) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL15418866 | 0.82 | DRD2 (0.57) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL15418864 | 0.82 | DRD2 (0.57) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8308892-B2 | Di-cinnamyl compounds and methods for use thereof | DESIGNER MOLECULES, INC. (US) | 2012-11-13 | — | — | US | disclosed |
| US-20090288768-A1 | DI-CINNAMYL COMPOUNDS AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. | 2009-11-26 | — | — | US | disclosed |
| US-20090288768-A1 | DI-CINNAMYL COMPOUNDS AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090288768-A1 | DI-CINNAMYL COMPOUNDS AND METHODS FOR USE THEREOF | CAD, DBF4, ACMSD | DRD2 1743/4885HTR2A 4135/4885HTR2C 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.