Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 5/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12572124 | 0.75 | ITGB3 (0.31) | — | |
| SCHEMBL24928556 | 0.75 | CAD (0.40) | LMNA | |
| SCHEMBL23260109 | 0.75 | CAD (0.40) | LMNA | |
| SCHEMBL25043983 | 0.75 | CAD (0.40) | LMNA | |
| SCHEMBL23870660 | 0.75 | CNR1 (0.44) | PRKCALMNANAAAFAAHCES2 | |
| SCHEMBL18949099 | 0.75 | CNR1 (0.44) | PRKCALMNANAAAFAAHCES2 | |
| SCHEMBL19334194 | 0.75 | CNR1 (0.44) | PRKCALMNANAAAFAAHCES2 | |
| SCHEMBL19387572 | 0.75 | CNR1 (0.44) | PRKCALMNANAAAFAAHCES2 | |
| SCHEMBL12236182 | 0.74 | APEX1 (0.33) | — | |
| SCHEMBL31295625 | 0.71 | LMNA (0.45) | PRKCALMNAPOLBCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778298-B2 | Isotope labeled 2-arylpropionic acid compounds and process for production of same, and molecular probe for positron emission tomography and method for imaging of cyclooxygenase and the like using same | RIKEN (JP) | 2014-07-15 | — | — | US | disclosed |
| US-7622440-B2 | Cyclic natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2009-11-24 | — | — | US | disclosed |