SCHEMBL12236182

SCHEMBL12236182

CN1CC(=O)N[C@@H](C(N)=O)C1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ APEX1 P27695 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ GAA P10253 1/20 0.32
▸ SORT1 Q99523 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23260109 0.83 CAD (0.40) BLM
SCHEMBL13435367 0.83 ITGB3 (0.31) —
SCHEMBL12572124 0.83 ITGB3 (0.31) —
SCHEMBL24928556 0.83 CAD (0.40) BLM
SCHEMBL13435368 0.83 ITGB3 (0.31) —
SCHEMBL25043983 0.83 CAD (0.40) BLM
SCHEMBL12236169 0.75 MEN1 (0.33) APEX1
SCHEMBL25251069 0.75 P2RX7 (0.39) GAASORT1
SCHEMBL13611121 0.74 PRKCA (0.40) —
SCHEMBL29005236 0.70 MMP13 (0.37) APEX1BLMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110263818-A1 Peptidic Constructs with Amino Acid Surrogates PALATIN TECHNOLOGIES, INC. (US) 2011-10-27 — — US disclosed
US-7964181-B2 Amino acid surrogates for peptidic constructs PALATIN TECHNOLOGIES, INC. (US) 2011-06-21 — — US disclosed
US-20070260040-A1 Amino Acid Surrogates for Peptidic Constructs PALATIN TECHNOLOGIES, INC. (US) 2007-11-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263818-A1 Peptidic Constructs with Amino Acid Surrogates ARGLU1, QRFPR, ARG1 APEX1 3312/4885BLM 4250/4885GAA 4085/4885
US-20070260040-A1 Amino Acid Surrogates for Peptidic Constructs ARGLU1, ARG1, QRFPR APEX1 3408/4885BLM 4492/4885GAA 4446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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