Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795179 | 0.85 | ALDH1A1 (0.46) | HTTKMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL3840210 | 0.82 | HSP90AB1 (0.45) | KMT2ATDP1L3MBTL1LMNANPC1 | |
| SCHEMBL16020932 | 0.82 | MAPT (0.38) | TAAR1HTTTYMPALDH1A1LMNA | |
| SCHEMBL82538 | 0.81 | TAAR1 (0.43) | HRH3TAAR1MEN1KMT2ATDP1 | |
| Water SCHEMBL10981448 | 0.80 | TAAR1 (0.42) | HRH3TAAR1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13611378 | 0.79 | LTA4H (0.46) | TDP1L3MBTL1ALDH1A1LMNANPC1 | |
| SCHEMBL13604291 | 0.79 | HRH3 (0.40) | HRH3HTR1DEPHX2TAAR1HTT | |
| Fluoride SCHEMBL28059937 | 0.79 | TAAR1 (0.41) | HRH3TAAR1MEN1KMT2ATDP1 | |
| SCHEMBL13604221 | 0.79 | HRH3 (0.42) | HRH3HTR1DEPHX2TAAR1ALDH1A1 | |
| SCHEMBL13611375 | 0.78 | CYP17A1 (0.43) | ALDH1A1LMNANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625921-B2 | Modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-12-01 | — | — | US | disclosed |