Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16325538 | 0.91 | KLK7 (0.49) | KLK7KLK5SYKCTSSCTSK | |
| SCHEMBL12880638 | 0.89 | SYK (0.43) | KLK7KLK5SYKCTSSCTSK | |
| SCHEMBL13613757 | 0.79 | CTSK (0.47) | SYKCTSSCTSKCTSLCTSB | |
| SCHEMBL12597519 | 0.79 | KLK7 (0.55) | KLK7KLK5SYKCTSSCTSK | |
| SCHEMBL4294019 | 0.79 | KLK7 (0.58) | KLK7KLK5SYKCTSSCTSK | |
| SCHEMBL4343773 | 0.78 | CTSK (0.48) | SYKCTSSCTSKCTSLCTSB | |
| SCHEMBL12231483 | 0.77 | SYK (0.43) | SYKCTSSCTSKPPARACTSL | |
| SCHEMBL9943562 | 0.76 | KLK5 (0.65) | KLK7KLK5SYKCTSSCTSK | |
| SCHEMBL344670 | 0.76 | PPARA (0.63) | KLK7KLK5SYKCTSSCTSK | |
| SCHEMBL344669 | 0.76 | PPARA (0.63) | KLK7KLK5SYKCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275727-A1 | Peptide turn mimetics | MIMETICA PTY LIMITED (AU) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275727-A1 | Peptide turn mimetics | IAPP, GLP1R, VIP | KLK7 283/4885KLK5 640/4885SYK 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.