Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2702564 | 0.86 | RAB9A (0.63) | POLBNR4A1RAB9AGAAMEN1 | |
| SCHEMBL4085443 | 0.83 | F2R (0.57) | ALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL17094866 | 0.82 | MAPT (0.45) | POLBNR4A1RAB9AGAAMEN1 | |
| SCHEMBL5199262 | 0.80 | MAOB (0.47) | POLBNR4A1RAB9AGAAMEN1 | |
| SCHEMBL5199245 | 0.80 | POLB (0.46) | POLBNR4A1RAB9AGAAMEN1 | |
| SCHEMBL2284477 | 0.79 | SMN1; SMN2 (0.59) | MEN1KMT2AALDH1A1MAPTCYP2C19 | |
| SCHEMBL14107963 | 0.79 | MAPT (0.58) | TERTPOLBRAB9AGAAMEN1 | |
| SCHEMBL7459466 | 0.78 | SOAT2 (0.59) | POLBRAB9ALMNASMN1; SMN2 | |
| SCHEMBL10780725 | 0.78 | SOAT2 (0.59) | POLBRAB9ALMNASMN1; SMN2 | |
| SCHEMBL19910360 | 0.77 | KMT2A (0.52) | RAB9AMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |