Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | UNG | P13051 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765844 | 0.84 | POLB (0.56) | JAK3GAAMEN1KMT2ALMNA | |
| SCHEMBL5199245 | 0.83 | POLB (0.46) | MAOBMAOAGAAMEN1KMT2A | |
| SCHEMBL2702564 | 0.83 | RAB9A (0.63) | GAAMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30827579 | 0.81 | PKM (0.63) | MAOBMAOAMEN1KMT2ALMNA | |
| SCHEMBL4085443 | 0.81 | F2R (0.57) | ALDH1A1MAPT | |
| SCHEMBL13614141 | 0.80 | TERT (0.55) | MAOBMAOAGAAMEN1KMT2A | |
| SCHEMBL1098080 | 0.80 | EPHX2 (0.65) | GAAMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3795376 | 0.80 | F2R (0.54) | MAOBMAOAGAAMEN1KMT2A | |
| SCHEMBL2284477 | 0.80 | SMN1; SMN2 (0.59) | MEN1KMT2AALDH1A1MAPTCYP2C19 | |
| SCHEMBL6959297 | 0.79 | UNG (0.53) | MAOBMAOAUNGALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469845-B1 | DERIVATIVES OF HALOACETAMIDOBENZOIC ACID AND USE THEREOF FOR THE TREATMENT OF PARASITIC DISEASES | KALIL FIHLO JORGE ELIAS (BR) | 2007-08-15 | — | — | EP | disclosed |
| EP-1469845-A2 | COMPOUNDS, PARTICULARLY OF UREA DERIVATIVES OR ESTER DERIVATIVES OF HALOACETAMIDOBENZOIC ACID AND USE THEREOF FOR THE TREATMENT OF PARASITIC DISEASES | Kalil-Fihlo, Jorge Elias (BR) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063858-A2 | COMPOUNDS, PARTICULARLY OF UREA DERIVATIVES OR ESTER DERIVATIVES OF HALOACETAMIDOBENZOIC ACID AND USE THEREOF FOR THE TREATMENT OF PARASITIC DISEASES | KALIL-FIHLO, JORGE, ELIAS (BR) | 2003-08-07 | — | — | WO | disclosed |