Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.72 |
| ▸ | P2RX4 | Q99571 | 6/20 | 0.72 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.72 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.65 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.65 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.64 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.63 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.63 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.63 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.63 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.59 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.59 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017388 | 1.00 | P2RX3 (0.72) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL13614589 | 0.85 | P2RY1 (0.83) | P2RX3P2RX4P2RX2P2RX1P2RY12 | |
| SCHEMBL13614594 | 0.85 | P2RY1 (0.83) | P2RX3P2RX4P2RX2P2RX1P2RY12 | |
| SCHEMBL14017382 | 0.85 | P2RY1 (0.83) | P2RX3P2RX4P2RX2P2RX1P2RY12 | |
| SCHEMBL14017387 | 0.85 | P2RY1 (0.83) | P2RX3P2RX4P2RX2P2RX1P2RY12 | |
| SCHEMBL5847481 | 0.84 | P2RX3 (0.74) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL5847412 | 0.84 | P2RX3 (1.00) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL5847211 | 0.81 | RNASEL (0.73) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL5848304 | 0.81 | ENPP1 (0.73) | P2RX3P2RX4P2RX2P2RX1P2RX7 | |
| SCHEMBL23922249 | 0.81 | P2RX3 (0.60) | P2RX3P2RX4P2RX2P2RX1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612047-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | DOUGLASS III JAMES G | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | PNKP, ENTPD5, ENPP1 | P2RX3 143/4885P2RX4 285/4885P2RX2 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.