Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 8/20 | 0.74 |
| ▸ | P2RX4 | Q99571 | 7/20 | 0.74 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.74 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.70 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.70 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.70 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.68 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.68 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.66 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.66 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.66 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.66 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.66 |
| ▸ | SRC | P12931 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848304 | 0.94 | ENPP1 (0.73) | P2RX3P2RX4P2RX2P2RY1P2RY2 | |
| SCHEMBL5847211 | 0.94 | RNASEL (0.73) | P2RX3P2RX4P2RX2P2RY1P2RY2 | |
| SCHEMBL22174968 | 0.86 | P2RX3 (0.73) | P2RX3P2RX4P2RX2P2RY1P2RY2 | |
| SCHEMBL19404164 | 0.86 | P2RX3 (0.73) | P2RX3P2RX4P2RX2P2RY1P2RY2 | |
| SCHEMBL26571082 | 0.85 | P2RX3 (0.68) | P2RX3P2RX4P2RX2P2RY1P2RY2 | |
| SCHEMBL5847412 | 0.85 | P2RX3 (1.00) | P2RX3P2RX4P2RX2P2RY1P2RY2 | |
| SCHEMBL27354771 | 0.85 | RNASEL (0.77) | P2RX3P2RX4P2RX2P2RY1P2RY2 | |
| SCHEMBL27354661 | 0.85 | RNASEL (0.77) | P2RX3P2RX4P2RX2P2RY1P2RY2 | |
| SCHEMBL14017388 | 0.84 | P2RX3 (0.72) | P2RX3P2RX4P2RX2P2RY1P2RY2 | |
| SCHEMBL13614604 | 0.84 | P2RX3 (0.72) | P2RX3P2RX4P2RX2P2RY1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084128-B2 | Method for reducing intraocular pressure | INSPIRE PHARMACEUTICALS, INC. (US) | 2006-08-01 | — | — | US | claimed |
| US-6881725-B2 | Method for treating pain | INSPIRE PHARMACEUTICALS INC. (US) | 2005-04-19 | — | — | US | claimed |
| US-20030186928-A1 | Method for reducing intraocular pressure | INSPIRE PHARMACEUTICALS, INC. | 2003-10-02 | — | — | US | claimed |
| EP-1348466-A2 | Method for treating pain with adenosine-tetraphosphates | Inspire Pharmaceuticals, Inc. (US) | 2003-10-01 | — | — | EP | claimed |
| US-20030158147-A1 | Method for treating pain | INSPIRE PHARMACEUTICALS INC. | 2003-08-21 | — | — | US | claimed |
| US-7084128-B2 | Method for reducing intraocular pressure | INSPIRE PHARMACEUTICALS, INC. (US) | 2006-08-01 | — | — | US | disclosed |
| US-6881725-B2 | Method for treating pain | INSPIRE PHARMACEUTICALS INC. (US) | 2005-04-19 | — | — | US | disclosed |
| US-20030186928-A1 | Method for reducing intraocular pressure | INSPIRE PHARMACEUTICALS, INC. | 2003-10-02 | — | — | US | disclosed |
| EP-1348466-A2 | Method for treating pain with adenosine-tetraphosphates | Inspire Pharmaceuticals, Inc. (US) | 2003-10-01 | — | — | EP | disclosed |
| US-20030158147-A1 | Method for treating pain | INSPIRE PHARMACEUTICALS INC. | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158147-A1 | Method for treating pain | P2RX2, P2RX3, P2RX5 | P2RX3 2/4885P2RX4 7/4885P2RX2 1/4885 |
| US-20030186928-A1 | Method for reducing intraocular pressure | P2RY1, P2RY11, P2RY6 | P2RX3 7/4885P2RX4 20/4885P2RX2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.