Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068691 | 0.75 | POLB (0.43) | L3MBTL1ATM | |
| SCHEMBL9510245 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL17039269 | 0.70 | EPHX1 (0.34) | — | |
| SCHEMBL10342267 | 0.64 | NPC1 (0.33) | — | |
| SCHEMBL14282687 | 0.64 | CTSK (0.41) | — | |
| SCHEMBL1248203 | 0.62 | DPP4 (0.34) | — | |
| SCHEMBL8941372 | 0.61 | — | — | |
| SCHEMBL17987718 | 0.61 | — | — | |
| SCHEMBL6039276 | 0.61 | — | — | |
| SCHEMBL9004534 | 0.61 | MMP1 (0.35) | L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193361-B2 | for plants; 2-(dibenzofuranyl-2-oxy)-2-methylthio-N-(2-methylpent-3-yn-2-yl)acetamide; 2-(indanyl-5-oxy)-2-methylthio-N-(2-methylpent-3-yn-2-yl)acetamide; 2-(3-phenylquinolinyl-6-oxy)-2-methylthio-N-(2-methylpent-3-yn-2-yl)acetamide; phytopathogenic fungi | SYNGENTA LIMITED (GB) | 2012-06-05 | — | — | US | disclosed |
| US-8067592-B2 | N-alkyny-2-(substituted aryloxy) alkylthioamine derivatives as fungicides | SYNGENTA LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |
| EP-1638928-B1 | N-ALKYNYL-2-(SUBSTITUTED ARYLOXY)ALKYLTHIOAMIDE DERIVATIVES AS FUNGICIDES | SYNGENTA LTD (GB) | 2010-09-29 | — | — | EP | disclosed |
| EP-1819689-B1 | 1-ALKYNYL-2-ARYLOXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-19 | — | — | EP | disclosed |
| US-20080096917-A1 | I-Alkynyl-2-Aryloxyalkylamides And Their Use As Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| US-20070042996-A1 | N-alkynyl-2-(substituted aryloxy) alkylthioamine derivatives as fungicides | SYNGENTA LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
| EP-1638928-A1 | N-ALKYNYL-2-(SUBSTITUTED ARYLOXY)ALKYLTHIOAMIDE DERIVATIVES AS FUNGICIDES | Syngenta Limited (GB) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004108663-A1 | N-ALKYNYL-2- (SUBSTITUTED ARYLOXY) ALKYLTHIOAMIDE DERIVATIVES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096917-A1 | I-Alkynyl-2-Aryloxyalkylamides And Their Use As Fungicides | DDT, CYP1A2, CYP51A1 | L3MBTL1 980/4885ATM 3439/4885 |
| US-20070042996-A1 | N-alkynyl-2-(substituted aryloxy) alkylthioamine derivatives as fungicides | NAT1, AKR7A2, KCNA2 | L3MBTL1 142/4885ATM 1229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.