Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614854 | 0.93 | ESR1 (0.40) | GPR84ALOX5ESR1ESR2MEN1 | |
| SCHEMBL13614847 | 0.91 | ALOX5 (0.41) | GPR84ALOX5ESR1ESR2MEN1 | |
| SCHEMBL12564879 | 0.87 | MEN1 (0.41) | GPR84ALOX5ESR1ESR2MEN1 | |
| SCHEMBL13614841 | 0.86 | GPR84 (0.45) | GPR84ALOX5ESR1ESR2KDM4E | |
| SCHEMBL13614845 | 0.83 | ALOX5 (0.41) | GPR84ALOX5ESR1ESR2KDM4E | |
| SCHEMBL13078982 | 0.83 | L3MBTL1 (0.45) | MEN1KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL13078994 | 0.83 | L3MBTL1 (0.45) | MEN1KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL13078939 | 0.83 | L3MBTL1 (0.45) | MEN1KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL13078995 | 0.83 | L3MBTL1 (0.45) | MEN1KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL13614824 | 0.82 | ALOX5 (0.49) | GPR84ALOX5ESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612204-B2 | Quinoxaline derivative, and light-emitting element and light-emitting device using quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-7612204-B2 | Quinoxaline derivative, and light-emitting element and light-emitting device using quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| WO-2008047589-A1 | QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE USING QUINOXALINE DERIVATIVE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2008-04-24 | — | — | WO | disclosed |
| US-20080091012-A1 | Quinoxaline Derivative, And Light-Emitting Element And Light-Emitting Device Using Quinoxaline Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
| US-20080091012-A1 | Quinoxaline Derivative, And Light-Emitting Element And Light-Emitting Device Using Quinoxaline Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080091012-A1 | Quinoxaline Derivative, And Light-Emitting Element And Light-Emitting Device Using Quinoxaline Derivative | NQO1, GLB1, PDXK | GPR84 913/4885ALOX5 549/4885ESR1 2358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.