SCHEMBL13614862

SCHEMBL13614862

CCCc1c(F)cc(-c2ccccc2F)cc1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.40
PTPN1 P18031 1/20 0.40
TNKS O95271 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
ERN1 O75460 1/20 0.37
GRIA4 P48058 3/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ADORA2A P29274 2/20 0.36
ADORA1 P30542 2/20 0.36
GCGR P47871 1/20 0.36
DHODH Q02127 1/20 0.36
ACMSD Q8TDX5 1/20 0.36
ALOX5AP P20292 1/20 0.36
FEN1 P39748 1/20 0.36
DRD2 P14416 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
CD274 Q9NZQ7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28916663 0.91 ERN1 (0.44) PTPRCPTPN1TNKSTNKS2ERN1
SCHEMBL19386822 0.81 ALDH1A1 (0.41) ALDH1A1MAPTL3MBTL1KDM4EGAA
SCHEMBL13615286 0.79 PTPRC (0.43) PTPRCPTPN1TNKSTNKS2ERN1
SCHEMBL10825673 0.76 GRIA4 (0.54) GRIA4ALDH1A1MAPTL3MBTL1GAA
SCHEMBL170879 0.75 TAAR1 (0.45) ALDH1A1KDM4EGAAHPGD
SCHEMBL12881753 0.75 HTR7 (0.53) PTPRCPTPN1DRD2
SCHEMBL19061356 0.75 PTGS1 (0.37) PTPN1ALDH1A1MAPTADORA2AADORA1
SCHEMBL28116695 0.75 PTPRC (0.54) PTPRCPTPN1TNKSTNKS2ERN1
SCHEMBL30990891 0.74 LTB4R (0.42) ALDH1A1GCGRCD274KDM4EGAA
SCHEMBL27999232 0.74 GCGR (0.40) PTPN1ALDH1A1MAPTGCGRCD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed