SCHEMBL136158

SCHEMBL136158

CCC(C(=O)ON1C(=O)CCC1=O)c1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 2/20 0.33
POLB P06746 2/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
CYP2D6 P10635 1/20 0.33
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23722658 0.91 ALDH1A1 (0.33) KDM4EALDH1A1HPGDMAPTKMT2A
SCHEMBL28692800 0.87 KMT2A (0.37) KDM4EALDH1A1HPGDMAPTKMT2A
SCHEMBL5352784 0.80 ALDH1A1 (0.36) KDM4EALDH1A1HPGDMAPTKMT2A
SCHEMBL38870 0.76 ALDH1A1 (0.44) KDM4EALDH1A1HPGDMAPTKMT2A
SCHEMBL10905515 0.76 ALDH1A1 (0.43) KDM4EALDH1A1HPGDMAPTKMT2A
SCHEMBL29439072 0.76 ALDH1A1 (0.44) KDM4EALDH1A1HPGDMAPTKMT2A
Pyrene SCHEMBL5535765 0.75 PSMB8 (0.38) KDM4EALDH1A1HPGDMAPTKMT2A
SCHEMBL5355184 0.75 ALDH1A1 (0.36) KDM4EALDH1A1HPGDMAPTKMT2A
SCHEMBL15389891 0.74 ALDH1A1 (0.42) KDM4EALDH1A1HPGDMAPTKMT2A
Succinimide SCHEMBL28533922 0.74 ALDH1A1 (0.36) KDM4EALDH1A1HPGDMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1949 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210275693-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC. 2021-09-09 US claimed
US-10961571-B2 Polymerase assay with a FRET substrate Life Technologies Corporation (US) 2021-03-30 US claimed
US-20190307904-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC (US) 2019-10-10 US claimed
EP-3541960-A2 METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS Quest Diagnostics Investments LLC (US) 2019-09-25 EP claimed
US-20190276904-A1 METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS QUEST DIAGNOSTICS INVESTMENTS LLC (US) 2019-09-12 US claimed
US-10301674-B2 Polymerase assay with a FRET substrate Life Technologies Corporation (US) 2019-05-28 US claimed
US-20190078133-A1 DETECTION AND IDENTIFICATION OF BACTERIA AND DETERMINATION OF ANTIBIOTIC SUSCEPTIBILITY USING BACTERIOPHAGE AND REPORTER MOLECULES CHARLES STARK DRAPER LABORATORY INC (US) 2019-03-14 US claimed
WO-2019051106-A1 DETECTION AND IDENTIFICATION OF BACTERIA AND DETERMINATION OF ANTIBIOTIC SUSCEPTIBILITY USING BACTERIOPHAGE AND REPORTER MOLECULES THE CHARLES STARK DRAPER LABORATORY INC. (US) 2019-03-14 WO claimed
US-20180136211-A1 METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS QUEST DIAGNOSTICS INVESTMENTS LLC (US) 2018-05-17 US claimed
EP-1427854-A1 METHODS FOR QUANTIFYING NUCLEAR RUN-ON TRANSCRIPTIONAL ASSAYS Benitec Australia Ltd. (AU) 2004-06-16 EP claimed
WO-2003018832-A1 METHODS FOR QUANTIFYING NUCLEAR RUN-ON TRANSCRIPTIONAL ASSAYS BENITEC AUSTRALIA LTD (AU) 2003-03-06 WO claimed
EP-4399327-A1 NON-SEQUENCING PCR-BASED METHOD FOR DETECTION OF ANTIBODY-CONJUGATED OLIGONUCLEOTIDES Becton, Dickinson and Company (US) 2024-07-17 EP disclosed
US-20240229117-A1 MULTIPLEXED PROTEIN AND NUCLEIC ACID DETECTION METHOD WITH ROLLING CIRCLE AMPLIFICATION (RCA) ASSISTED COLOR COMBINATORIAL AND SEQUENTIAL FLUORESCENCE IN SITU HYBRIDIZATION (CCS-FISH) THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-07-11 US disclosed
WO-2024148227-A2 LAMP DETECTION OF AFRICAN SWINE FEVER VIRUS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2024-07-11 WO disclosed
US-20240229137-A9 Oligonucleotide-Comprising Cellular Component-Binding Reagents and Methods of Using the Same BECTON, DICKINSON AND COMPANY 2024-07-11 US disclosed
US-6271002-B1 A POLYMERASE CHAIN REACTION KIT FOR INCORPORATING AN RNA POLYMERASE PROMOTER INTO DOUBLE STRANDED CDNA BY AMPLIFICATION WITH AN RNA PRIMER FOR LESS THAN 20 CYCLES; THEN THE RNA POLYMERASE CONTAINING CDNA IS THEN TRANSCRIBED INTO RNA ROSETTA INPHARMATICS, INC. 2001-08-07 US disclosed
WO-2001038570-A1 OLIGONUCLEOTIDES AND ASSEMBLIES THEREOF USEFUL IN THE DETECTION OF THE PRESENCE OR ABSENCE OF TARGET NUCLEIC ACID SEQUENCES IN A SAMPLE GAMIDA SENSE DIAGNOSTICS LTD. (IL) 2001-05-31 WO disclosed
WO-2001016375-A2 HIGH SPEED PARALLEL MOLECULAR NUCLEIC ACID SEQUENCING THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2001-03-08 WO disclosed
WO-2000050643-A2 METHOD FOR DETECTING RADIATION EXPOSURE THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2000-08-31 WO disclosed
US-6090552-A DETECTING TELOMERASE ACTIVITY BY CONTACTING SAMPLE WITH PRIMERS, ONE HAVING LABELS AND SUBSTRATE FOR ENZYME, OTHER COMPLEMENTARY TO TELOMERIC REPEATS; ALLOWING ENZYME ACTIVITY; AMPLIFYING NUCLEIC ACIDS; DETECTING/MEASURING EMITTED ENERGY INTERGEN COMPANY (US) 2000-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190307904-A1 MODIFIED WOUND DRESSINGS MMP8, CD68, ELANE KDM4E 2928/4885ALDH1A1 393/4885HPGD 279/4885
US-20210275693-A1 MODIFIED WOUND DRESSINGS MMP8, CD68, ELANE KDM4E 2928/4885ALDH1A1 393/4885HPGD 279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.