SCHEMBL13616944

SCHEMBL13616944

COc1cc(CCC[Si](C)(O[Si](C)(C)C)O[Si](C)(CCCc2ccccc2)O[Si](C)(C)O[Si](C)(C)C)ccc1C

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
EBP Q15125 2/20 0.40
SIGMAR1 Q99720 2/20 0.40
TMEM97 Q5BJF2 1/20 0.40
PLAAT3 P53816 1/20 0.39
PLAAT5 Q96KN8 1/20 0.39
PLAAT2 Q9NWW9 1/20 0.39
PLAAT4 Q9UL19 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12349736 0.95 EBP (0.43) ALOX5EBPSIGMAR1TMEM97PLAAT3
SCHEMBL12349745 0.88 ALOX5 (0.56) ALOX5
SCHEMBL13616943 0.88 MTNR1A (0.46) ALOX5
SCHEMBL12349859 0.83 IGF1R (0.43) ALOX5HPGD
SCHEMBL12349742 0.82 ALOX5 (0.57) ALOX5
SCHEMBL12349730 0.82 MTNR1A (0.49) ALOX5
SCHEMBL13616947 0.80 TAAR1 (0.51) ALOX5
SCHEMBL13616969 0.79 CETP (0.38) SIGMAR1HPGD
SCHEMBL12349758 0.79 PLAAT3 (0.47) ALOX5SIGMAR1PLAAT3PLAAT5PLAAT2
SCHEMBL12349748 0.78 LTA4H (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090276042-A1 Biological Polysiloxanes VISION CRC LIMITED (AU) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090276042-A1 Biological Polysiloxanes PBK, B2M, CD79B ALOX5 899/4885EBP 1032/4885SIGMAR1 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.