Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.63 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630689 | 0.94 | ALDH1A1 (0.61) | FAAHSLC6A5ALDH1A1ITGB3ITGA2B | |
| SCHEMBL20414922 | 0.82 | FAAH (0.69) | FAAHSLC6A5ALDH1A1ITGB3ITGA2B | |
| SCHEMBL424500 | 0.82 | FAAH (0.76) | FAAHSLC6A5ALDH1A1ITGB3ITGA2B | |
| SCHEMBL13963521 | 0.82 | ITGB3 (0.68) | FAAHALDH1A1ITGB3ITGA2B | |
| SCHEMBL9954851 | 0.82 | FAAH (0.76) | FAAHSLC6A5ALDH1A1ITGB3ITGA2B | |
| SCHEMBL424501 | 0.82 | FAAH (0.76) | FAAHSLC6A5ALDH1A1ITGB3ITGA2B | |
| SCHEMBL15649626 | 0.82 | FAAH (0.76) | FAAHSLC6A5ALDH1A1ITGB3ITGA2B | |
| SCHEMBL31026947 | 0.82 | FAAH (0.76) | FAAHSLC6A5ALDH1A1ITGB3ITGA2B | |
| SCHEMBL424499 | 0.82 | FAAH (0.76) | FAAHSLC6A5ALDH1A1ITGB3ITGA2B | |
| SCHEMBL22494098 | 0.82 | FAAH (0.91) | FAAHSLC6A5ITGB3ITGA2BEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | ELLNEUROXX LTD. (DE) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | HTT, NLN, SNCA | FAAH 4423/4885SLC6A5 859/4885ALDH1A1 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.