Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617024 | 0.94 | FAAH (0.63) | ALDH1A1ALOX15ITGB3ITGA2BFAAH | |
| SCHEMBL13963521 | 0.87 | ITGB3 (0.68) | ALDH1A1ITGB3ITGA2BFAAHNOD1 | |
| SCHEMBL13630692 | 0.83 | ALOX15 (0.62) | ALDH1A1ALOX15ITGB3ITGA2B | |
| SCHEMBL1215264 | 0.82 | ALOX15 (0.58) | ALDH1A1ALOX15ITGB3ITGA2BFAAH | |
| SCHEMBL1214323 | 0.80 | ALOX15 (0.56) | ALDH1A1ALOX15ITGB3ITGA2BFAAH | |
| SCHEMBL24090396 | 0.80 | TRPV1 (0.62) | ALDH1A1ALOX15ITGB3ITGA2BFAAH | |
| SCHEMBL8257309 | 0.80 | TRPV1 (0.62) | ALDH1A1ALOX15ITGB3ITGA2BFAAH | |
| SCHEMBL3452191 | 0.79 | FAAH (0.67) | ALDH1A1ITGB3ITGA2BFAAHNOD1 | |
| SCHEMBL4581440 | 0.79 | FAAH (0.67) | ALDH1A1ITGB3ITGA2BFAAHNOD1 | |
| SCHEMBL4582828 | 0.79 | FAAH (0.67) | ALDH1A1ITGB3ITGA2BFAAHNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | ELLNEUROXX LTD. (DE) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | HTT, NLN, SNCA | ALDH1A1 4155/4885ALOX15 392/4885ITGB3 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.