Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348734 | 0.86 | PDE4B (0.45) | KMT2ASMN1; SMN2F10TPSAB1 | |
| SCHEMBL302010 | 0.85 | F10 (0.51) | KMT2AF10TPSAB1TP53NAMPT | |
| SCHEMBL12919536 | 0.83 | F10 (0.41) | ALDH1A1F10TPSAB1TP53NAMPT | |
| SCHEMBL301585 | 0.83 | MEN1 (0.46) | ALDH1A1KMT2AMAPTF10TPSAB1 | |
| SCHEMBL15866724 | 0.80 | ACHE (0.49) | TPSAB1 | |
| SCHEMBL12919537 | 0.79 | F10 (0.53) | ALDH1A1LMNAKMT2AMAPTF10 | |
| SCHEMBL13830591 | 0.77 | QDPR (0.45) | LMNATPSAB1TP53NAMPT | |
| SCHEMBL14898046 | 0.76 | NPC1L1 (0.44) | TPSAB1NAMPT | |
| SCHEMBL13830794 | 0.76 | TPSAB1 (0.44) | ALDH1A1KMT2ATPSAB1MEN1 | |
| SCHEMBL14879910 | 0.76 | L3MBTL3 (0.44) | TPSAB1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723140-B1 | PROCESS FOR THE PREPARATION OF TRYPTASE INHIBITORS | AVENTIS PHARMA INC (US) | 2009-11-04 | — | — | EP | disclosed |