Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | DUT | P33316 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16427979 | 0.76 | LMNA (0.49) | ALDH1A1KCNN4KIF11DUTSMN1; SMN2 | |
| SCHEMBL11133561 | 0.75 | ALOX5 (0.53) | ALDH1A1MAPTMEN1KMT2AHDAC3 | |
| SCHEMBL14286704 | 0.74 | TDP1 (0.53) | ALDH1A1MAPTKCNN4KIF11MEN1 | |
| SCHEMBL30625928 | 0.74 | KIF11 (0.56) | MAPTKCNN4KIF11KMT2ADUT | |
| SCHEMBL11203911 | 0.73 | ALOX5 (0.53) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL7430087 | 0.73 | TDP1 (0.56) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11210249 | 0.72 | MAPT (0.54) | ALDH1A1MAPTHDAC1HDAC2SMN1; SMN2 | |
| SCHEMBL11204989 | 0.72 | MAPT (0.54) | ALDH1A1MAPTHDAC1HDAC2SMN1; SMN2 | |
| SCHEMBL11209239 | 0.72 | MAPT (0.54) | ALDH1A1MAPTHDAC1HDAC2SMN1; SMN2 | |
| SCHEMBL11204332 | 0.72 | MAPT (0.54) | ALDH1A1MAPTHDAC1HDAC2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311488-B1 | SUBSTITUTED IMIDAZOLES AS TAFIA INHIBITORS | PFIZER LTD (GB) | 2009-11-04 | — | — | EP | disclosed |