Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 2/20 | 0.42 |
| ▸ | JUN | P05412 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617331 | 0.89 | HDAC1 (0.40) | HDAC1HDAC2 | |
| SCHEMBL12954586 | 0.80 | LTB4R (0.34) | MAPTLMNAGAAL3MBTL1 | |
| SCHEMBL13389072 | 0.79 | NPC1 (0.47) | FOSJUNNR1H4MAPTTP53 | |
| SCHEMBL13617337 | 0.72 | NPSR1 (0.39) | NPSR1 | |
| SCHEMBL13389068 | 0.70 | NPC1 (0.46) | FOSJUNNR1H4MAPTTP53 | |
| SCHEMBL13389098 | 0.67 | MAPK14 (0.43) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL12218332 | 0.64 | NPC1 (0.68) | NR1H4MAPTTP53SMN1; SMN2NPC1 | |
| SCHEMBL25039727 | 0.62 | ALDH1A1 (0.56) | FOSJUNNR1H4MAPTSMN1; SMN2 | |
| SCHEMBL15651852 | 0.61 | SMN1; SMN2 (0.57) | NR1H4MAPTTP53SMN1; SMN2NPC1 | |
| SCHEMBL1527292 | 0.61 | FOS (1.00) | FOSJUNNR1H4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133831-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | 旭化成ファーマ株式会社 (JP) | 2009-11-05 | — | — | WO | disclosed |