Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617336 | 0.89 | FFAR4 (0.33) | FFAR4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL13617333 | 0.78 | NR1H4 (0.33) | FFAR4 | |
| SCHEMBL13617331 | 0.75 | HDAC1 (0.40) | — | |
| SCHEMBL13389126 | 0.74 | TRPA1 (0.46) | NPSR1FFAR4 | |
| SCHEMBL13617334 | 0.72 | FOS (0.42) | NPSR1 | |
| SCHEMBL12954586 | 0.67 | LTB4R (0.34) | FFAR4FFAR1 | |
| SCHEMBL12954587 | 0.65 | — | — | |
| SCHEMBL1011231 | 0.64 | CCNC (0.40) | — | |
| SCHEMBL13389425 | 0.64 | ROCK2 (0.43) | FFAR4 | |
| SCHEMBL13389074 | 0.63 | TRPA1 (0.44) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133831-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | 旭化成ファーマ株式会社 (JP) | 2009-11-05 | — | — | WO | disclosed |