Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946891 | 0.84 | NPC1 (0.61) | NPC1RAB9ATHRBMAPTL3MBTL1 | |
| SCHEMBL19958473 | 0.81 | NPC1 (0.69) | NPC1RAB9ATHRBMAPTL3MBTL1 | |
| SCHEMBL1567479 | 0.80 | FTO (0.61) | NPC1RAB9ATHRBMAPTL3MBTL1 | |
| SCHEMBL14451198 | 0.78 | PTPN11 (0.46) | NPC1RAB9ATHRBMAPTL3MBTL1 | |
| SCHEMBL13239215 | 0.77 | PTPN11 (0.45) | NPC1RAB9ATHRBMAPTL3MBTL1 | |
| SCHEMBL13861529 | 0.75 | MAPT (0.43) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| Resorcin Brown SCHEMBL31650975 | 0.75 | RPS6KA3 (0.59) | NPC1RAB9ATHRBMAPTMAPK1 | |
| Resorcin Brown SCHEMBL110507 | 0.75 | RPS6KA3 (0.59) | NPC1RAB9ATHRBMAPTMAPK1 | |
| Resorcin Brown SCHEMBL110506 | 0.75 | RPS6KA3 (0.59) | NPC1RAB9ATHRBMAPTMAPK1 | |
| Resorcin Brown SCHEMBL185545 | 0.74 | THRB (0.53) | NPC1RAB9ATHRBMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280147-A1 | Compositions comprising dye-loaded particles | NOXELL CORPORATION | 2009-11-12 | — | — | US | disclosed |
| US-20090263658-A1 | Dye-loaded particles | THE PROCTER & GAMBLE COMPANY | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280147-A1 | Compositions comprising dye-loaded particles | CD68, ASAH2, SORT1 | NPC1 188/4885RAB9A 1650/4885THRB 4845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.