Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617879 | 0.87 | HTR6 (0.59) | HTR6POLBPKMCA1CA2 | |
| SCHEMBL28271796 | 0.85 | HTR6 (0.83) | HTR6POLBPKMCYP19A1CA1 | |
| SCHEMBL28271807 | 0.81 | HTR6 (0.71) | HTR6POLBPKMCA1CA2 | |
| SCHEMBL2723618 | 0.80 | HTR6 (1.00) | HTR6POLBPKMCA1CA2 | |
| SCHEMBL13412107 | 0.80 | PGR (0.52) | HTR6HSPD1HSPE1 | |
| Hydrochloric Acid SCHEMBL18953392 | 0.79 | HTR6 (0.97) | HTR6POLBPKMCA1CA2 | |
| SCHEMBL30737484 | 0.78 | PGR (0.71) | HTR6POLBPKMCYP19A1KMT2A | |
| SCHEMBL30737540 | 0.78 | HTR6 (0.71) | HTR6POLBPKMCA1CA2 | |
| SCHEMBL16199439 | 0.78 | HTR6 (0.71) | HTR6POLBPKMCA1CA2 | |
| SCHEMBL28271830 | 0.78 | HTR6 (0.71) | HTR6POLBPKMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817296-B1 | POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2009-11-04 | — | — | EP | disclosed |