Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.71 |
| ▸ | HTR6 | P50406 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | CCR2 | P41597 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16431575 | 1.00 | PGR (0.71) | PGRHTR6POLBPKMMEN1 | |
| SCHEMBL28539211 | 0.89 | HTR6 (0.69) | PGRHTR6POLBPKMMEN1 | |
| SCHEMBL28271796 | 0.89 | HTR6 (0.83) | PGRHTR6POLBPKMKMT2A | |
| SCHEMBL30737524 | 0.86 | HTR6 (0.79) | HTR6POLBMEN1KMT2ACYP19A1 | |
| SCHEMBL28271815 | 0.86 | HTR6 (0.79) | HTR6POLBMEN1KMT2ACYP19A1 | |
| SCHEMBL28121847 | 0.86 | PGR (0.73) | PGRPOLBPKMLMNAMAPT | |
| SCHEMBL2723618 | 0.83 | HTR6 (1.00) | PGRHTR6POLBPKMMEN1 | |
| SCHEMBL3756876 | 0.83 | PGR (1.00) | PGRPOLBPKMMEN1KMT2A | |
| SCHEMBL28513724 | 0.83 | HTR6 (0.69) | PGRHTR6POLBPKMMEN1 | |
| SCHEMBL343776 | 0.83 | HTR6 (0.73) | PGRHTR6PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510460-A | Benzo [ b ] thiophene derivative containing sulfonamide unit, and preparation method and application thereof | 贵州大学 | 2024-02-06 | — | — | CN | disclosed |