Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617420 | 0.87 | HTR6 (0.66) | HTR6PKMPOLBKMT2ACA1 | |
| SCHEMBL18382568 | 0.84 | KEAP1 (0.76) | HTR6KEAP1PKMPOLBKMT2A | |
| SCHEMBL13412105 | 0.82 | AR (0.55) | HTR6PKMCA1CA2PGR | |
| SCHEMBL28121844 | 0.80 | PKM (0.72) | HTR6KEAP1PKMPOLBKMT2A | |
| SCHEMBL18382566 | 0.80 | KEAP1 (0.69) | HTR6KEAP1PKMPOLBKMT2A | |
| SCHEMBL13618096 | 0.78 | HTR6 (0.48) | HTR6POLBKMT2A | |
| SCHEMBL29118882 | 0.77 | PGR (0.65) | HTR6KEAP1PKMPOLBKMT2A | |
| SCHEMBL28121847 | 0.77 | PGR (0.73) | KEAP1PKMPOLBPGR | |
| SCHEMBL3081180 | 0.76 | KEAP1 (1.00) | HTR6KEAP1PKMPOLBKMT2A | |
| SCHEMBL13412107 | 0.75 | PGR (0.52) | HTR6PGRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817296-B1 | POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2009-11-04 | — | — | EP | disclosed |